Dr Jitendra lauds Christian Medical College Vellore for successful Haemophilia gene therapy

Excelsior Correspondent
VELLORE, Oct 10: Union Minister of Science and Technology Dr. Jitendra Singh today inaugurated at the Christian Medical College (CMC), Vellore, the 10th Annual “Cell and Gene Therapy” Symposium organised by the Centre for Stem Cell Research (CSCR), supported by the Department of Biotechnology, Govt of India.
The Union Minister also inaugurated a new 42-bed Medium-Cost Private Ward in the Department of Psychiatry.
Dr. Jitendra Singh lauded the landmark achievement of CSCR, which recently completed India’s first-in-human gene therapy trial for Hemophilia A. The inherited bleeding disorder, caused by the deficiency of clotting Factor VIII, has long required costly lifelong treatment. CSCR’s approach, using lentiviral vectors instead of the commonly used AAV, expanded patient eligibility and showed sustained Factor VIII expression with no bleeding episodes.
The Minister noted that CSCR, a translational unit of inStem, Bengaluru, under the Department of Biotechnology (DBT), is preparing for the next phase of clinical development. “Several technologies for hemoglobinopathies are being transferred to commercial partners, and CSCR is building a GMP-compliant haplobank of iPSCs as part of the Global Alliance for iPSC Therapies,” he added.
Dr. Jitendra Singh said, the new psychiatry ward strengthens CMC’s legacy of mental health care, which dates back to the 1950s. The medium-cost facility has been designed to serve patients across socioeconomic groups. “The Department of Psychiatry already runs three key wards – the fully subsidised Annexe Ward, the partly subsidised Low-Cost Private Ward, and the Private Ward whose revenues sustain the others. But many of the private ward rooms, built in the 1950s, are now structurally outdated. This new ward responds to that need, adding 42 beds that meet modern safety standards and provide the highest quality of psychiatric care,” he said.
The Minister emphasised that the ward balances affordability with excellence. “By fostering a nurturing environment that encourages family participation in the healing process, this facility will elevate patient care while also ensuring subsidised treatment for underprivileged communities,” he added.
Placing these developments in the national context, Dr. Jitendra Singh said, in biomanufacturing India today stands at Rank 3 in Asia-Pacific and Rank 12 globally, while pharma exports expected to cross 300 billion USD by the turn of this year.
Dr. Jitendra Singh underscored that India’s innovation ecosystem is being strengthened by policies and programmes such as the BioE3 policy, BIRAC’s public-private model, the National Research Foundation with 70% non-government funding, and a Rs 1 lakh crore R&D fund to support private sector participation. He said Gross Expenditure on R&D has doubled from Rs 60,000 crore to Rs 1,27,000 crore, while the DBT budget has risen from Rs 1,500 crore to nearly Rs 7,000 crore, with over 55% of patents now filed by Indian residents.
Concluding, Dr. Jitendra Singh said the two inaugurations reflect India’s twin focus on expanding affordable mental health services and advancing cutting-edge scientific innovation. “Affordable, accessible, and quality healthcare, whether physical or mental, is essential for building a self-reliant India. The achievements at CMC and CSCR exemplify how our institutions are driving innovation to meet the aspirations of India@2047,” he said.

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